Guillaume Germain
Education
M.Sc. and B.Sc., economics, University of Quebec at Montreal
Summary of Experience
Mr. Germain specializes in health economics and outcomes research (HEOR). He has extensive experience in retrospective database/claims analyses; clinical efficacy, safety profile, treatment patterns, and medication compliance studies; and biostatistics, epidemiology, and health outcomes research with advanced statistical methods, such as survival analysis, general estimating equations, and nonparametric testing. Mr. Germain has conducted research on a broad range of diseases and conditions, including asthma, chronic obstructive pulmonary disease, bipolar disorder, major depressive disorder, atrial fibrillation, venous thromboembolism, cancer, schizophrenia, and hepatitis C. His research has been presented at international conferences including those of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), the Academy of Managed Care Pharmacy (AMCP), the American Heart Association (AHA), and the American Association for the Study of Liver Diseases (AASLD). Mr. Germain’s research and analyses have been published in peer-reviewed journals including The Oncologist, the Journal of Asthma, the Journal of Chronic Obstructive Pulmonary Disease, Clinical Therapeutics, and the Journal of Medical Economics.
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Evaluating the real-world effectiveness of belimumab in patients with SLE using SLE-related laboratory values and rheumatoid arthritis-derived disease activity measures: RAPID3, swollen joint count and tender joint count
Lupus Science & Medicine, 2024
2024Germain G, Worley K, MacKnight SD, Rubin B, Bell CF, Laliberté F, Urosevic A, Duh MS, Concoff A
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Real-world association between systemic corticosteroid exposure and complications in US patients with severe asthma
Allergy, Asthma & Clinical Immunology, 2024
2024Casale TB, Corbridge T, Germain G, Laliberté F, MacKnight SD, Boudreau J, Duh MS, Deb A
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Real-world users of triple therapy for asthma in the US
American Journal of Managed Care, 2024
2024Hansel NN, Abbott CB, Averell CM, Germain G, Laliberté F, Mahendran M, Duh MS, Settipane RA
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A 5-Year Retrospective, Observational Study Assessing Rheumatoid Arthritis Disease Outcome Measures to Characterize Systemic Lupus Erythematosus Burden in the USA
Rheumatology and Therapy, 2023
2023Bell CF, Huang SP, Yu LH, DerSarkissian M, Germain G, Concoff AL, Averell CM, Rubin B, Gu YM, Duh MS, Wallace DJ
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Real-World Study of Single-Inhaler Triple Therapy with Fluticasone Furoate/Umeclidinium/Vilanterol on Asthma Control in the US
Journal of Asthma and Allergy, 2023
2023Bogart M, Germain G, Laliberté F, Mahendran M, Duh MS, DiRocco K, Noorduyn SG, Paczkowski R, Balkissoon R
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Comparing Real-World Healthcare Costs Associated with Single-Tablet Regimens for HIV-1: The 2-Drug Regimen Dolutegravir/Lamivudine vs. Standard 3- or 4-Drug Regimens
Infectious Diseases and Therapy, 2023
2023Priest J, Germain G, Laliberté F, Duh MS, Mahendran M, Fakih I, Oglesby A
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Real-World Treatment Patterns and Switching Following Moderate/Severe Chronic Obstructive Pulmonary Disease Exacerbation in Patients with Commercial or Medicare Insurance in the United States
International Journal of Chronic Obstructive Pulmonary Disease, 2023
2023Bogart M, Germain G, Laliberté F, Lejeune D, Duh MS
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Impact of adherence to treatment with inhaled corticosteroids/long-acting β-agonists on asthma outcomes in the United States
Therapeutic Advances in Respiratory Disease, 2022
2022Averell CM, Laliberté F, Germain G, Duh MS, Rousculp MD, MacKnight SD, Slade DJ
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The real-world health resource use and costs of misdiagnosing bipolar I disorder
Journal of Affective Disorders, 2022
2022McIntyre RS, Laliberté F, Germain G, MacKnight SD, Gillard P, Harrington A
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Adherence and Persistence to Single-Inhaler Versus Multiple-Inhaler Triple Therapy for Asthma Management
The Journal of Allergy and Clinical Immunology: In Practice, 2022
2022Busse WW, Abbott CB, Germain G, Laliberté F, MacKnight SD, Jung Y, Duh MS, Averell CM
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Symptom control in patients with asthma using inhaled corticosteroids/long-acting β2-agonists (fluticasone furoate/vilanterol or budesonide/formoterol) in the US: a retrospective matched cohort study
Journal of Asthma, 2022
2022Averell CM, Laliberté F, Germain G, Duh MS, Lima R, Mahendran M, Slade DJ
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Benefit of Prompt versus Delayed Use of Single-Inhaler Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Following a COPD Exacerbation
International Journal of Chronic Obstructive Pulmonary Disease, 2022
2022Mannino D, Bogart M, Germain G, Huang SP, Ismaila AS, Laliberté F, Jung Y, MacKnight SD, Stiegler MA, Duh MS
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Real-World Prostate-Specific Antigen Response and Treatment Adherence of Apalutamide in Patients with Non-Metastatic Castration-Resistant Prostate Cancer
Urology, 2022
2022Lowentritt B, Brown G, Pilon D, Ellis L, Germain G, Rossi C, Lefebvre P, Kernen K, Sieber P, Shore N
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Disease burden and treatment adherence among children and adolescent patients with asthma
Journal of Asthma, 2022
2022Averell CM, Laliberté F, Germain G, Slade DJ, Duh MS, Spahn J
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Elucidating the Real-World Burden of Chronic Rhinosinusitis with Nasal Polyps in Patients in the USA
OTO Open, 2022
2022Benson VS, Germain G, Chan RH, Sousa AR, Yang S, Silver J, Duh MS, Laliberté F, Chang R, Han JK
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Real-World Healthcare Resource Utilization in Patients with Classical Hodgkin Lymphoma Treated with Pembrolizumab and Nivolumab in the USA
Targeted Oncology, 2021
2021Laliberté F, Raut M, Yang X, Germain G, Nahar A, Desai KD, MacKnight SD, Sen SS, Duh MS
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Umeclidinium/Vilanterol Compared with Fluticasone Propionate/Salmeterol, Budesonide/Formoterol, and Tiotropium as Initial Maintenance Therapy in Patients with COPD Who Have High Costs and Comorbidities
International Journal of Chronic Obstructive Pulmonary Disease, 2021
2021Kalhan R, Slade D, Ray R, Moretz C, Germain G, Laliberté F, Shen Q, Duh MS, MacKnight SD, Hahn B
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Real-World Characteristics, Treatment Patterns, Health Care Resource Use, and Costs of Patients with Diffuse Large B-Cell Lymphoma in the U.S.
The Oncologist, 2021
2021Yang X, Laliberté F, Germain G, Raut M, Duh MS, Sen SS, Lejeune D, Desai K, Armand P
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Real-world impact of antiepileptic drug combinations with versus without perampanel on healthcare resource utilization in patients with epilepsy in the United States
Epilepsy & Behavior, 2021
2021Laliberté F, Duh MS, Barghout V, Germain G, Frech F, Plauschinat C, Lejeune D, Malhotra M, Faught E
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Treatment patterns, healthcare resource utilization, and costs of patients diagnosed with primary mediastinal B-cell lymphoma in the United States
Journal of Medical Economics, 2021
2021Yang X, Laliberté F, Germain G, Raut M, Duh MS, Sen SS, Lejeune D, Desai K, Armand P
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Time-to-first exacerbation, adherence, and medical costs among US patients receiving umeclidinium/vilanterol or tiotropium as initial maintenance therapy for chronic obstructive pulmonary disease: a retrospective cohort study
BMC Pulmonary Medicine, 2021
2021Slade D, Ray R, Moretz C, Germain G, Laliberté L, Shen Q, Duh MS, Mahendran M, Hahn B
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Cancer associated thrombosis and mortality in patients with cancer stratified by khorana score risk levels
Cancer Medicine, 2020
2020Khorana AA, Kuderer NM, McCrae K, Milentijevic D, Germain G, Laliberté F, MacKnight SD, Lefebvre P, Lyman GH, Streiff MB
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Real-World Adherence in Patients with Metastatic Colorectal Cancer Treated with Trifluridine plus Tipiracil or Regorafenib
Oncologist, 2020
2020Patel AK, Barghout V, Yenikomshian MA, Germain G, Jacques P, Laliberté F, Duh MS
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Healthcare costs of stroke and major bleeding in patients with atrial fibrillation treated with non-vitamin K antagonist oral anticoagulants
Journal of Medical Economics, 2019
2019Rozjabek HM, Coleman CI, Ashton V, Laliberté F, Oyefesobi P, Lejeune D, Germain G, Schein JR, Yuan Z, Lefebvre P, Peterson ED
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Modeling the impact of real-world adherence to once-daily (QD) versus twice-daily (BID) non-vitamin K antagonist oral anticoagulants on stroke and major bleeding events among non-valvular atrial fibrillation patients
Current Medical Research and Opinion, 2019
2019McHorney CA, Peterson ED, Ashton V, Laliberté F, Crivera C, Germain G, Sheikh N, Schein J, Lefebvre P
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Medication adherence in patients with asthma using once-daily versus twice-daily ICS/LABAs
Journal of Asthma, 2019
2019Averell CM, Stanford RH, Laliberté F, Wu JW, Germain G, Duh MS
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Medication adherence and persistence in chronic obstructive pulmonary disease patients receiving triple therapy in a USA commercially insured population
International Journal of Chronic Obstructive Pulmonary Disease, 2019
2019Bogart M, Stanford RH, Laliberté F, Germain G, Wu JW, Duh MS
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Characterizing Real-World Use Of Tiotropium In Asthma In The USA
Journal of Asthma and Allergy, 2019
2019Averell CM, Laliberté F, Duh MS, Wu JW, Germain G, Faison S
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Risk of Ischemic Stroke in Patients Newly Diagnosed With Heart Failure: Focus on Patients Without Atrial Fibrillation
Journal of Cardiac Failure, March 26, 2018
2018Berger JS, Peterson E, Laliberté F, Germain G, Lejeune D, Schein J, Lefebvre P, Zhao Q, Weir MR
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Adherence to rivaroxaban versus apixaban among patients with non-valvular atrial fibrillation: Analysis of overall population and subgroups of prior oral anticoagulant users
PLOS One. 2018 Apr 5;13(4):e0194099
2018McHorney CA, Crivera C, Laliberté F, Germain G, Wynant W, Lefebvre P
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Effects of Systemic Corticosteroids on Blood Eosinophil Counts in Asthma: Real-World Data
Journal of Asthma. 2018 Oct 16:1-8
2018Ortega H, Llanos JP, Lafeuille MH, Duh MS, Germain G, Lejeune D, Sama S, Bell C, Hahn B
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Burden of disease associated with a COPD eosinophilic phenotype
International Journal of Chronic Obstructive Pulmonary Disease. 2018 Aug 13;13:2425-2433
2018Ortega H, Llanos JP, Lafeuille MH, Germain G, Duh MS, Bell CF, Sama SR, Hahn B
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Health characteristics of patients with asthma, COPD and asthma-COPD overlap in the NHANES database
International Journal of Chronic Obstructive Pulmonary Disease. 2018 Sep 12;13:2859-2868
2018Llanos JP, Ortega H, Germain G, Duh MS, Lafeuille MH, Tiggelaar S, Bell CF, Hahn B
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Treatment persistence and hospitalization rates among patients with schizophrenia: a quasi-experiment to evaluate a patient information program
Current Medical Research and Opinion. Apr 2017;33(4):713-721
2017Pilon D, Amos TB, Germain G, Lafeuille MH, Lefebvre P, Benson CJ
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Health care resource utilization before and after perampanel initiation among patients with epilepsy in the United States
Epilepsia. Jul 25 2017
2017Faught E, Laliberté F, Wang Z, Barghout V, Haider B, Lejeune D, Germain G, Choi J, Wagh A, Duh MS
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Stroke risk reduction outweighed bleeding risk increase from vitamin K antagonist treatment among nonvalvular atrial fibrillation patients with high stroke risk and low bleeding risk
Current Medical Research and Opinion. Apr 2017;33(4):631-638
2017Nelson WW, Laliberté F, Patel AA, Germain G, Pilon D, McCormick N, Lefebvre P
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Prasugrel vs. clopidogrel in acute coronary syndrome patients treated with prasugrel
Journal of Clinical Pharmacology & Therapeutics, December 2014, Vol. 39, No. 6
2014Olson WH, Ma YW, Laliberte F, Lefebvre P, Crivera C, Schein JR, Fields LE, Dea K, Germain G, Lynch SM
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Impact of completing chronic hepatitis C (CHC) treatment on post-therapy healthcare cost
Journal of Medical Economics, December 2014, Vol. 17, No. 12
2014Tandon N, Balart LA, Laliberte F, Pilon D, Lefebvre P, Germain G, Prabhakar A
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Is rivaroxaban associated with lower inpatient costs compared to warfarin among patients with non-valvular atrial fibrillation?
Current Medical Research & Opinion, August 2014, Vol. 30, No. 8
2014Laliberte F, Pilon D, Raut MK, Nelson WW, Olson WH, Germain G, Schein JR, Lefebvre P
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Hospital length of stay of nonvalvular atrial fibrillation
Hospital Practice, August 2014, Vol. 42, No. 3
2014Laliberte F, Pilon D, Raut MK, Nelson WW, Olson WH, Germain G, Schein JR, Lefebvre P
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Hospital length of stay: is rivaroxaban associated with shorter inpatient stay compared to warfarin among patients with non-valvular atrial fibrillation?
Current Medical Research & Opinion, April 2014, Vol. 30, No. 4
2014Laliberte F, Pilon D, Raut MK, Nelson WW, Olson WH, Germain G, Schein JR, Lefebvre P
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December 4, 2024
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April 4, 2024
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October 19, 2023
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March 2, 2023
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December 7, 2022
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October 15, 2021
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April 13, 2021